Sickle Cell Disease
Management of Vaso-Occlusive Crisis and Acute Chest Syndrome
Pain Management
What is the best pharmacologic treatment for sickle cell disease pain crises? (opens new window)
Source: Ann Emerg Med 2012;59(6):515-6.
Indexed: PubMed 22221839
DOI: 10.1016/j.annemergmed.2011.11.026
https://www.ncbi.nlm.nih.gov/pubmed/22221839 (opens new window)
Update on pain management in sickle cell disease. (opens new window)
Source: Hemoglobin 2011;35(5-6):520-9.
Indexed: PubMed 21910604
DOI: 10.3109/03630269.2011.610478
https://www.ncbi.nlm.nih.gov/pubmed/21910604 (opens new window)
Reduction of painful vaso-occlusive crisis of sickle cell anaemia by tinzaparin in a double-blind randomized trial. (opens new window)
Source: Thromb Haemost 2007;98(2):392-6.
Indexed: PubMed 17721622
https://www.ncbi.nlm.nih.gov/pubmed/17721622 (opens new window)
Adult emergency department patients with sickle cell pain crisis: results from a quality improvement learning collaborative model to improve analgesic management. (opens new window)
Source: Acad Emerg Med 2012;19(4):430-8.
Indexed: PubMed 22506947
DOI: 10.1111/j.1553-2712.2012.01330.x
https://www.ncbi.nlm.nih.gov/pubmed/22506947 (opens new window)
Hydration Therapy (Fluid Management)
Management of sickle cell disease. (opens new window)
Source: BMJ 2008;337:a1397.
Indexed: PubMed 18779222
https://www.ncbi.nlm.nih.gov/pubmed/18779222 (opens new window)
Fluid replacement therapy for acute episodes of pain in people with sickle cell disease. (opens new window)
Source: Cochrane Database Syst Rev 2012;(6):CD005406.
Indexed: PubMed 22696351
DOI: 10.1002/14651858.CD005406.pub3
https://www.ncbi.nlm.nih.gov/pubmed/22696351 (opens new window)
Oxygen Supplementation
Low flow nocturnal oxygen therapy does not suppress haemoglobin levels or increase painful crises in sickle cell disease. (opens new window)
Source: Br J Haematol 2013;161(3):455-6.
Indexed: PubMed 23419066
DOI: 10.1111/bjh.12254
https://www.ncbi.nlm.nih.gov/pubmed/23419066 (opens new window)
Guidelines for the management of the acute painful crisis in sickle cell disease. (opens new window)
Source: Br J Haematol 2003;120(5):744-52.
Indexed: PubMed 12614204
https://www.ncbi.nlm.nih.gov/pubmed/12614204 (opens new window)
Hyperbaric oxygen therapy for vaso-occlusive crises in nine patients with sickle-cell disease. (opens new window)
Source: Diving Hyperb Med 2012;42(2):82-4.
Indexed: PubMed 22828815
https://www.ncbi.nlm.nih.gov/pubmed/22828815 (opens new window)
Antibiotic and Respiratory Therapy
Safety of purified poloxamer 188 in sickle cell disease: phase I study of a non-ionic surfactant in the management of acute chest syndrome. (opens new window)
Source: Hemoglobin 2004;28(2):85-102.
Indexed: PubMed 15182051
https://www.ncbi.nlm.nih.gov/pubmed/15182051 (opens new window)
Incentive spirometry to prevent acute pulmonary complications in sickle cell diseases. (opens new window)
Source: N Engl J Med 1995;333(11):699-703.
Indexed: PubMed 7637747
DOI: 10.1056/NEJM199509143331104
https://www.ncbi.nlm.nih.gov/pubmed/7637747 (opens new window)
Continuous inhaled nitric oxide therapy in a case of sickle cell disease with multiorgan involvement. (opens new window)
Source: J Investig Med 2008;56(8):1023-7.
Indexed: PubMed 19050460
DOI: 10.2310/JIM.0b013e31818cb612
https://www.ncbi.nlm.nih.gov/pubmed/19050460 (opens new window)
Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. (opens new window)
Source: N Engl J Med 2000;342(25):1855-65.
Indexed: PubMed 10861320
DOI: 10.1056/NEJM200006223422502
https://www.ncbi.nlm.nih.gov/pubmed/10861320 (opens new window)